More recently, it has been shown that, still via the ANS, a peripheral inflammation can induce the appearance in the insular cortex, of inflammation-specific engrams associated with specific ensemble of neurons
Effects are characterized in animal models: potent antinociception, catalepsy at higher amounts, and dose-dependent respiratory and blood-pressure changes typical of a mu-opioid
10.1089/ars.2009.2671 Summary Keywords prematurity, extrauterine growth restriction (EUGR), antioxidants, catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), children Citation Ordez-Daz MD, Gil-Campos M, Flores-Rojas K, Muoz-Villanueva MC, Mesa MD, de la Torre-Aguilar MJ, Gil and Prez-Navero JL (2021) Impaired Antioxidant Defence Status Is Associated With Metabolic-Inflammatory Risk Factors in Preterm Children With Extrauterine Growth Restriction: The BIORICA Cohort Study
Answer: While the product itself has no noted side effects, some individuals may experience mild skin sensitivity or irritation when using glutathione-based creams